[heckel NEWS LETTER] 2021년 7월호

마케팅팀 2022.07.26 조회 173
1) ICHO-Webinar presented by heckel: "Progress of Hyperthermia in the Treatment of Locally Recurrent Breast Cancer” -  Full length record available

In May 2021, a successful ICHO-Webinar took place on "Progress of Hyperthermia in the Treatment of Locally Recurrent Breast Cancer (LRBC)".
The Webinar is available in full via this link: https://www.icho2021.eu/programm/programme


Chair: Desiree van den Bongard, MD, PhD, Dept. of Radiation Oncology, Amsterdam University Medical Centers

Hans Crezee, PhD, Dept. of Radiation Oncology, Amsterdam University Medical Centers:
Meta-analysis of clinical data of combined HT/RT in the treatment of LRBC (10 minutes summary)

Markus Notter, MD, Radiation Oncology, Lindenhofspital Bern:
Combined wIRA hyperthermia and hypofractionated re-RT for LRBC patients

Andreas Thomsen, MD, Dept. of Radiation Oncology, University Medical Center Freiburg:
Practical handling and troubleshooting of superficial, thermography-controlled wIRA-HT

Hans Crezee, PhD, Dept. of Radiation Oncology, Amsterdam University Medical Centers:
Role of MW-HT and wIRA-HT for different situations of LRBC and possible combinations
2) New (German) publikation on "Radiotherapy and hyperthermia for breast cancer" in Der Gynäkologe
In June 2021, a German article on the treatment of inoperable locally recurrent of breast cancer with radiotherapy and hyperthermia appeared in the "Der Gynäkologe" (SPRINGER journal).

Mirko Nitsche1 · Jürgen Dunst2 · David Krug2 · Ralf Meyer3 · Robert Michael Hermann1, 4

1. Zentrum für Strahlentherapie und Radioonkologie Bremen und Westerstede, Bremen, Deutschland
2. Klinik für Strahlentherapie, Universitätsklinikum Schleswig-Holstein (UKSH), Kiel, Deutschland
3. Hämatologie und Onkologie am Medicum, Bremen, Deutschland
4. Strahlentherapie und Spezielle Onkologie, Medizinische Hochschule, Hannover, Deutschland

Strahlentherapie mit Hyperthermie beim Mammakarzinom (Radiotherapy and hyperthermia for breast cancer)

In addition to the presentation of basic scientific data on superficial hyperthermia and radiotherapy for breast cancer, the classification of locally recurrent breast cancer into specific size classes as proposed by Notter et al. 2020 is presented. The method of the contact-free, thermography-guided wIRA hyperthermia is described in detail. This technique is also available at Zentrum für Strahlentherapie und Radioonkologie Bremen und Westerwede.

3) Obituary of Dr. rer. nat. habil. Debra Kelleher
On 17 May 2021, after a long illness, Debra K. Kelleher, Ph.D. passed away.

For more than 17 years, from 1991 - 2008, Dr Kelleher was a close colleague of Prof. Peter Vaupel at the Institute of Physiology & Pathophysiology at the University Medical Center Mainz, first as a postdoc, later as a working group leader.  In 2008 she habilitated in pathophysiology.

Debra Kelleher is the author/co-author of 60 Pubmed-listed, highly regarded publications, including 15 fundamental preclinical papers on the effect of water-filtered infrared A radiation (wIRA). This work includes studies on the influence of wIRA on blood flow, oxygen supply and the microenvironment of malignant tumours, as well as studies on the combination of photodynamic therapy and wIRA hyperthermia. In 1991, she co-authored the first communication on the use of wIRA in oncological superficial hyperthermia.

The systematic preclinical wIRA research at the Institute of Physiology & Pathophysiology of the University Medical Center Mainz was an indispensable condition for the development and clinical use of thermography-controlled wIRA superficial hyperthermia.
We are deeply indebted to her and will continue to honour her memory.

Selected publications related to oncological hyperthermia: 

Vaupel P, Kelleher DK, Krüger W. Water-filtered infrared-A radiation: a novel technique to heat superficial tumors.
Strahlenther Onkol. 1992 Nov;168(11):633-9. PUBMED

Kelleher DK, Engel T, Vaupel PW. Changes in microregional perfusion, oxygenation, ATP and lactate distribution in subcutaneous rat tumours upon water-filtered IR-A hyperthermia.
Int J Hyperthermia. 1995 Mar-Apr;11(2):241-55. PUBMED

Vaupel PW, Kelleher DK: Pathophysiological and vascular characteristics of tumours and their importance for hyperthermia: heterogeneity is the key issue.
Int J Hyperthermia. 2010;26(3):211-23. PUBMED

Vaupel PW, Kelleher DK: Blood flow and associated pathophysiology of uterine cervix cancers: characterisation and relevance for localised hyperthermia.
Int J Hyperthermia. 2012;28(6):518-27. PUBMED

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